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Illinois starting running back Josh Ferguson will not play in Saturday's game at Iowa due to a right shoulder injury, the team announced Thursday.
The senior back did not return to Saturday's game against Nebraska after a 2-yard loss late in the first quarter.
The Illini (4-1, 1-0 in Big Ten) senior had 50 yards on four carries before leaving the game. He rushed for a season-high 133 yards against North Carolina -- his only 100-plus yard game this season -- and racked up 381 yards on 71 carries and three touchdowns while making 12 catches for 78 yards.
It's not the first time Ferguson has dealt with injuries. He received a medical redshirt during his first season at Illinios after missing nine games with a hamstring injury. Following that he has played in 33 straight games, dating back to the 2012 season.
True freshman running back Ke'Shawn Vaughn will get the start. Vaughn ran for a career-high 98 yards on 24 carriers and caught one pass in the 14-13 comeback win for Illinois. The Antioch, Tenn. native has 325 yards on 76 carries and two touchdowns in five games this season.
If #illini get to 5-1 with an injury list that includes this many key contributors... pic.twitter.com/0EjYJxRnyE
— Jeremy Werner (@JWernerScout) October 8, 2015
The Illini travel to Iowa City to play the Hawkeyes (5-0, 1-0) on Saturday in a Big Ten West division clash.